I have been having issues on this particuliar server, no server had issues except this one with KB4343900 for Windows 2008 R2 with following error 80070020
I had tried that before once some years ago on a server and went bad, lost connectivity and was on remote site.
So I always avoid the clean state boot, but I guess decided to try this time, 'cos this server is full of MySQL, Apache, IIS, lots of Framework stuff, I thought always could help.
And it did! :)
Thanks for your help and time spent looking on my server logs!!