My newest PCs in the office are Win7 64 bit, and yes, they're fast. Give people a large or dual monitor setup, and they're in heaven. I have had some minor issues with legacy equipment, however, such as Dymo labelmakers. We have a couple in our office, and they're still quite functional, but older models aren't compatible with Win7, and Dymo has no intention of fixing that issue. I have 2 that are becoming obsolete as I upgrade, and I find that frustrating. The good thing is that we also just migrated to a new system that combines project management, quoting, ordering, and invoicing in one system, including the ability to drag email attachments and other documents into it. This has negated the need to keep project files, which has negated the need to print labels for the files. The system being replaced doesn't run all that well on Win7 either, so the migration came at a good time.
I will say that from a support standpoint, setting up a new Win7 on the network is much faster than XP, so deployment is easier. Since I'm a department of one, that works in my favor.