I have a Dell G5 and I'm experiencing the same problems. Dropouts every 20 minutes or so with an external sound interface, only when I was connected to the internet.
I believe I've fixed the issue by disabling or stopping most of the Dell services and applications, as well as something called PC-Doctor. I'm no computer expert so I don't know what I did, but I haven't had any dropout for more than 24h so far.
I still get one or two pops but only over long periods. I'm using Cakewalk and a Focusrite 4i4.